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Also, glutamate-derived glutamine production through GS activity could be another mechanism to overcome glutamine addiction and to promote resistance to glutaminolysis inhibitors [85]

This increases blood flow, possibly helping with RLS

Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced inflammatory bowel disease

Endothelial dysfunction in HIV infection: experimental and clinical evidence on the role of oxidative stress

Integrating these approaches with conventional treatments such as phototherapy or topical corticosteroids may offer a comprehensive therapeutic strategy to manage vitiligo by protecting melanocytes from oxidative stress and ferroptosis (136)

The functional importance of intracellular communication mediated by EVs has been studied by several researchers